Endocrine Abstracts

Background: Parathyroid carcinoma accounts for <1% of cases of primary hyperparathyroidism. Clinical presentation is usually related to severe hypercalcemia associated to elevated serum PTH (three times above the upper limit). These values are so much higher than in primary hyperparathyroidism due to a benign adenoma. Moreover, 30–75% of patients had a palpable neck mass.Clinical case: Fifty one-year-old male, submitted to bariatric surgery by a...

Introduction: Blood glucose control during pregnancy is essential in patients with gestational diabetes (GD) to prevent fetal complications. Despite advances in its control, neonatal morbidity and mortality still appears in a significant percentage of cases. The presence of GD also implies consequences for the mother, as the GD appearance in a new pregnancy and/or the future development of glucose metabolism alterations.Methods: We conducted a retrospect...

Introduction: Gestational diabetes (GD) is frequently associated with obesity and family history of diabetes. Besides these, other risks factors have been proposed, as previous GD, macrosomy or abnormal reproductive history.Methods: We conducted a retrospective comparative study including all patients diagnosed of GD during 1999 and 2008. The analyzed variables were incidence and risk factors of GD.Results: We included 384 patients...

Background: Patients with diabetes insipidus (DI) that suffer of adipsia usually are difficult to treat, and requiring close monitorization.Aim: To know long-term outcome of patients with DI associated to adipsia.Subjects: From January 1989 to December 2006 were attended five patients (two males) with DI plus adipsia, aged 32±14.64 years, range 10–51. Being the aetiology X histiocytosis, craneapharyngioma, suprasellar men...

Background: Classic 21-hydroxylase deficiency, due to severe mutations in CYP21B gene, is an uncommon disease (1/ 150 000). Salt-wasting form accounts for 75% of the cases and turns up with gluco- and mineralocorticoid deficiency as well as feminine hermaphroditism. Although wide psycho-social repercussion especially in women is known, the rarity of the disease and losses in follow-up may lead to a scarce clinical experience. We present 3 adult patients with CAH- SW followed r...